Christina Applegate shared a raw health update with her fans this week. The actress explained that stress can severely worsen her multiple sclerosis symptoms. Her post offered a stark look at living with the autoimmune disease.

She revealed a recent stressful event led to a significant physical decline. The “Dead to Me” star said she had fallen multiple times as a result.
Actress Uses Social Media to Raise Awareness
Applegate posted a short, powerful video on Instagram. In the caption, she directly addressed people who may not understand MS. She wrote that stress or emotional upset can make symptoms dramatically worse.
She described her legs as “busted” after several falls. Her message urged more compassion for those with chronic illnesses. Support from fellow celebrities like Jennifer Love Hewitt flooded the comments section.
According to Reuters, multiple sclerosis affects the central nervous system. Symptoms vary widely but often include fatigue, mobility issues, and numbness.
A Long and Private Health Battle
Christina Applegate first publicly disclosed her MS diagnosis in 2021. This announcement forced a five-month production hiatus on the final season of her Netflix show. She needed time to begin treatment.
She has since revealed her symptoms began years earlier. On her “MeSsy” podcast, she recalled collapsing on set during the “Dead to Me” pilot. She now recognizes that fall as an early sign of the disease.
The show’s creator, Liz Feldman, recalled noticing Applegate’s balance issues. She initially attributed it to long filming hours. Feldman later sensed something more serious was happening.
Committing to Openness Amid Daily Challenges
Applegate continues to speak with remarkable honesty about her condition. She has discussed experiencing severe pain and deep depression. Her openness provides a vital window into life with a progressive neurological disorder.
Her latest post underscores the invisible daily struggles MS patients face. It highlights the direct link between emotional well-being and physical symptoms. This advocacy work brings crucial attention to the need for greater public understanding.
Her candid discussion continues to shed light on the realities of living with multiple sclerosis, fostering a much-needed conversation about chronic illness and empathy.
Info at your fingertips
What is multiple sclerosis?
Multiple sclerosis is an autoimmune disease. It affects the brain and spinal cord. The condition disrupts communication between the brain and the body.
When was Christina Applegate diagnosed with MS?
She announced her diagnosis publicly in August 2021. She has since revealed her symptoms appeared years earlier. The diagnosis paused filming for her Netflix series.
What are common MS symptoms?
Common symptoms include severe fatigue and difficulty walking. Numbness, muscle weakness, and vision problems are also frequent. Symptoms often flare up with stress.
How has MS affected her career?
It required a production break on “Dead to Me.” She now uses a cane for mobility at public events. She has shifted focus to podcasting and advocacy work.
Why is stress a trigger for MS?
Stress can worsen inflammation in the body. This exacerbates existing neurological damage. It often leads to a noticeable increase in physical symptoms.
Trusted Sources: Reuters, Associated Press, BBC
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