Brock Purdy Injury Update: 49ers QB Ruled Out vs. Rams With Toe Issue

San Francisco 49ers quarterback Brock Purdy has been ruled out for Thursday night’s crucial NFC West showdown against the Los Angeles Rams. The move comes after the starter struggled with a recurring toe injury and missed key practices this week.

The 49ers confirmed the decision late Wednesday, ending hopes of a surprise return. Backup Mac Jones will lead the offense in Purdy’s place as San Francisco tries to stay competitive in the tight division race.

Brock Purdy Injury Update: Official Team Confirmation

Purdy originally injured his toe in Week 1 and has been on and off the 49ers’ injury report ever since. He missed Weeks 2 and 3, returned for Week 4 against Jacksonville, but reported increased soreness after the game. According to reports from NFL.com and AP, Purdy sat out both Tuesday and Wednesday practices before the team officially ruled him out.

It’s the quarterback’s third missed start this season. When Jones filled in earlier, he delivered two wins — including a 26-21 road victory over the New Orleans Saints and a tight 16-15 home win against the Arizona Cardinals. The team will look for a similar performance Thursday night against the Rams.

The 49ers’ injury list remains long. Wide receivers Jauan Jennings (ankle/ribs) and Ricky Pearsall (knee) are out, while George Kittle stays on injured reserve. Star wideout Brandon Aiyuk is still recovering from a major knee injury, and defensive end Robert Beal Jr. will also miss the game. This leaves the offense without several key playmakers.

Impact on the 49ers’ Season Outlook

Without Purdy and multiple receivers, San Francisco is expected to rely heavily on Christian McCaffrey to carry the load. Quick passes, screen plays, and a run-focused plan could dominate the playbook as head coach Kyle Shanahan tries to protect Jones and keep the offense moving.

Long term, Purdy’s toe injury raises concerns about durability. Turf-related toe issues can linger and affect push-off power for quarterbacks. The team will monitor his recovery closely to avoid further setbacks. How the 49ers manage this stretch could define their playoff positioning in the NFC West.

In short, the Brock Purdy injury update means Mac Jones gets another chance to steer the 49ers. But the team faces major depth challenges against a tough Rams defense.

FYI (keeping you in the loop)-

Q1: Will Brock Purdy play next week?

It’s uncertain. His return depends on how the toe responds to rest and treatment over the coming days.

Q2: How long has Purdy been dealing with this injury?

Since Week 1. He missed two games earlier this season before briefly returning in Week 4.

Q3: Who will start for the 49ers against the Rams?

Mac Jones will make his third start of the season while Purdy recovers.

Q4: What other 49ers players are injured?

Jauan Jennings, Ricky Pearsall, George Kittle, and Robert Beal Jr. are also out. Brandon Aiyuk is still recovering from a knee injury.

Q5: Is this a turf toe injury?

Yes, reports describe it as a form of turf toe — an injury that can take time to fully heal.