Marlyne Barrett is leaving the hit NBC series Chicago Med. Her departure coincides with the show’s upcoming 10-year anniversary. The actress played Charge Nurse Maggie Lockwood since the series premiere in 2015.

This exit marks a significant shift for the long-running medical drama. Only two original cast members now remain as the show prepares to celebrate a major legacy milestone.
Barrett’s Final Episode and Cast Reshuffle
Barrett announced her exit in late August 2025. She is stepping away for personal reasons. According to Variety, her character was a cornerstone of the emergency department.
Showrunner Allen MacDonald has indicated her leave could be temporary. This leaves the door open for Maggie Lockwood’s potential return in future episodes.
The timing is particularly poignant. Her departure was confirmed just one day after Nick Gehlfuss announced his guest return as Dr. Will Halstead. This creates a mix of emotions for the dedicated fanbase.
Impact on Chicago Med’s Legacy and Future
Barrett’s exit profoundly changes the dynamic at Gaffney Chicago Medical Center. She was one of only three original cast members still on the show. Her character provided emotional stability and institutional knowledge.
Maggie Lockwood served as the heart of the ED for a decade. She guided new interns and supported senior staff through countless crises. Her absence creates a substantial void in the show’s core identity.
The series must now navigate its milestone season without a key original player. This tests the resilience of the long-running One Chicago franchise. The remaining original cast, S. Epatha Merkerson and Oliver Platt, now carry the show’s foundational legacy.
Chicago Med continues its eleventh season amid these significant cast changes. The show’s ability to evolve will determine its future beyond this celebratory year.
Thought you’d like to know-
Is Marlyne Barrett leaving Chicago Med permanently?
Her departure is currently for personal reasons. The showrunner has left the possibility open for a return. Her status is best described as a temporary leave.
Who are the original cast members still on Chicago Med?
Only S. Epatha Merkerson and Oliver Platt remain as original cast members. They play Sharon Goodwin and Dr. Daniel Charles, respectively. Their characters now anchor the show’s history.
When did Chicago Med first premiere?
The series premiered on November 17, 2015. The show will celebrate its 10-year anniversary in late 2025. This milestone coincides with its 200th episode.
Is Nick Gehlfuss returning to Chicago Med?
Yes, he will guest star in the 200th episode. He is reprising his role as Dr. Will Halstead. This marks his first appearance since leaving the series.
How many episodes of Chicago Med have aired?
The series will reach its 200th episode during Season 11. This is a significant achievement for a primetime network drama. It reflects the show’s enduring popularity.
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