Chris O’Donnell Eyes Grey’s Anatomy Co-Stars For New 9-1-1: Nashville Crossover

Chris O’Donnell wants his old colleagues on his new show. The actor shared his hopes for a crossover event. He spoke at the premiere of 9-1-1: Nashville in Tennessee.

The star revealed which former castmates he thinks would fit perfectly. He mentioned working with Jessica Capshaw again already. This news excites fans of both popular television franchises.

From Seattle Grace to Nashville’s First Responders

O’Donnell spoke with PEOPLE magazine at the W Hotel event. He plays Captain Don Sharpe on the new ABC procedural. The show premiered on October 9th.

He named several former co-stars from the medical drama. Sandra Oh and Patrick Demsey were on his list. Ellen Pompeo was also mentioned as a potential guest star.

The actor reflected on the long passage of time. His stint on Grey’s Anatomy was twenty years ago. He expressed fondness for his former colleagues.

A Reunion Years in the Making

This potential crossover highlights a small Hollywood world. O’Donnell already shares the screen with Jessica Capshaw. She played Arizona Robbins on Grey’s Anatomy for ten seasons.

Both actors also overlapped on The Practice years ago. O’Donnell noted the coincidence is fun. It shows how interconnected television casts can be.

The actor’s comments have sparked immediate fan speculation online. Viewers are now imagining storylines. A crossover event could bring significant ratings to both shows.

Chris O’Donnell’s vision for a 9-1-1: Nashville crossover taps into deep fan nostalgia. It could create a major television event linking two beloved ABC universes.

Thought you’d like to know-

Who did Chris O’Donnell specifically mention from Grey’s Anatomy?

He named Sandra Oh, Patrick Dempsey, and Ellen Pompeo. He spoke fondly of his time working with them. O’Donnell noted he hasn’t seen Dempsey in years.

Is Jessica Capshaw already on 9-1-1: Nashville?

Yes, Jessica Capshaw is a series regular. She plays a first responder on the show. This marks another project where she and O’Donnell have worked together.

When did Chris O’Donnell appear on Grey’s Anatomy?

He guest-starred in seasons 2 and 3. His character was a love interest for Ellen Pompeo’s Meredith Grey. That was approximately twenty years ago.

When does 9-1-1: Nashville air?

The new show airs every Wednesday. It is on ABC at 9 p.m. Eastern Time. The series premiered on October 9, 2025.

What other show did O’Donnell and Capshaw both appear on?

They both had roles on the legal drama *The Practice*. O’Donnell referenced this overlap during his interview. He called Hollywood a “small world.”