Christian McCaffrey Dominates Cardinals in Three-Touchdown Blowout

Christian McCaffrey delivered a stunning performance against the Arizona Cardinals. The San Francisco 49ers star running back scored three touchdowns in a commanding 41-22 victory. The game took place on November 16, 2025, at State Farm Stadium.This win solidifies the 49ers’ position as a playoff contender. According to ESPN, McCaffrey extended his NFL record for career games with both a rushing and receiving touchdown.

Breaking Down McCaffrey’s Historic Performance

McCaffrey’s impact was immediate and decisive. He scored his first touchdown on a one-yard run just moments into the game. This set a dominant tone for the 49ers’ offense from the opening drive.He later added a nine-yard receiving touchdown from quarterback Brock Purdy. McCaffrey capped his day with a four-yard rushing score in the second half. His final stat line included 121 total yards from scrimmage.Purdy’s return from a toe injury was seamless. He completed 19 of 26 passes for 200 yards and three touchdowns. The 49ers’ offense operated with high efficiency throughout the contest.

Why McCaffrey’s Versatility Reshapes the 49ers’ Offense

McCaffrey’s dual-threat capability presents a unique challenge for opposing defenses. He can exploit weaknesses in both the run and pass game. This versatility forces defenses to remain honest in their schemes.The Cardinals struggled to contain McCaffrey in all phases. Their defensive game plan appeared unprepared for his diverse skill set. This performance demonstrates why he remains among the league’s most valuable offensive weapons.San Francisco’s record improves to 7-4 with this crucial divisional win. They maintain strong positioning in the NFC West race. The team’s offensive balance makes them a formidable opponent heading into the season’s final stretch.

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Christian McCaffrey’s record-breaking day against the Cardinals proves his elite status remains unquestioned as the 49ers build crucial momentum for their playoff push.

Thought you’d like to know

How many touchdowns does Christian McCaffrey have this season?

McCaffrey now has 11 total touchdowns through 11 games this season. His scoring pace places him among the league leaders. He continues to be a primary red-zone weapon for San Francisco.

What record did McCaffrey extend with this performance?

He extended his NFL record for career games with both a rushing and receiving touchdown. This was his 17th such game. The record highlights his unique dual-threat capability.

How did Brock Purdy perform in his return from injury?

Purdy delivered an efficient performance in his return. He completed 19 of 26 passes for 200 yards and three touchdowns. His connection with McCaffrey proved particularly effective.

What was significant about the Cardinals’ performance?

Arizona set a franchise record with 17 penalties during the game. The team has now lost six of its last seven games. Discipline issues continue to plague their season.

What’s next for the San Francisco 49ers?

The 49ers host the Carolina Panthers on Monday, November 24. This marks McCaffrey’s first game against his former team this season. The matchup carries significant playoff implications for both clubs.