The medical cause of death for Cleto Escobedo III has been officially confirmed. The longtime bandleader for “Jimmy Kimmel Live!” passed away earlier this month at 59. His death certificate lists cardiogenic shock as the immediate cause.

This condition occurs when the heart suddenly cannot pump enough blood to the body. The news follows an emotional tribute from host Jimmy Kimmel, his childhood friend.
Underlying Health Conditions Contributed to His Passing
According to a report from TMZ, the death certificate details several contributing factors. Escobedo also suffered from vasodilatory shock and disseminated intravascular coagulation. These conditions severely compromise circulation and blood clotting.
He was also diagnosed with alcoholic cirrhosis of the liver. Additional underlying issues included sepsis, pneumonia, and chronic kidney disease. The combination of these ailments created an insurmountable health crisis.
The information provides a clearer, though tragic, picture for fans and loved ones. It confirms the bandleader faced a complex and serious medical situation in his final days.
A Legacy Remembered Through Charity and Friendship
In the wake of his passing, Jimmy Kimmel has focused on honoring his friend’s legacy. He recently launched two fundraising initiatives in Escobedo’s name. One benefits the UCLA Medical Center, where Escobedo received care.
The other supports The Animal Foundation, reflecting Escobedo’s love for animals. This charitable response highlights the positive impact Escobedo had on those around him. It turns grief into actionable support for causes he cared about.
Fans have widely praised the deep, enduring friendship between the two men. Their bond, which began in their youth in Las Vegas, was a cornerstone of the show’s identity for nearly two decades.
The revelation of Cleto Escobedo’s cause of death closes a painful chapter for his family and friends. His memory continues to inspire acts of kindness and support, ensuring his spirit lives on through the music and community he loved.
Thought you’d like to know
What was Cleto Escobedo’s official cause of death?
His death certificate lists cardiogenic shock as the immediate cause. This means his heart failed to pump sufficient blood. The condition was compounded by other serious health issues.
What other health conditions did he have?
He also suffered from vasodilatory shock, liver cirrhosis, and sepsis. His medical record included chronic kidney disease and pneumonia. These conditions collectively contributed to his passing.
How is Jimmy Kimmel honoring Cleto Escobedo?
Kimmel started fundraisers for UCLA Medical Center and The Animal Foundation. These initiatives celebrate Escobedo’s life and his kindness. They aim to help patients and animals in need.
How long was Cleto Escobedo the bandleader?
He led the show’s band, Cleto and the Cletones, since its start in 2003. His tenure lasted for over two decades. He was a foundational part of the program’s identity.
Who did Cleto Escobedo leave behind?
He is survived by his wife, Lori, and their two children. His daughter is named Jesse and his son is named Cruz. The family has requested privacy during this time.
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