Fantasy Football Injury Update Week 13: Which Player Concerns Matter Most?

Fantasy Football Injury Update Week 13 arrives with major questions surrounding key starters across the league. Several teams released new practice reports on November 26, revealing fresh concerns and potential returns. These updates are critical for managers preparing for the final stretch of the season.

Multiple high-impact players are dealing with shoulder, ankle, knee, and concussion issues this week. Coaches and team officials have confirmed new timelines, upgrades, and setbacks. These updates shape lineup decisions for thousands of fantasy managers heading into Week 13.

Latest Injury Developments for Fantasy Football Injury Update Week 13

Week 13 features notable news on quarterbacks, running backs, and receivers who play central roles in fantasy lineups. Baker Mayfield is dealing with a sprained AC joint in his non-throwing shoulder and is expected to miss this week. This shifts the Buccaneers’ offense to Teddy Bridgewater, reducing the fantasy floor of every primary pass catcher.

Isiah Pacheco returns from a knee injury after missing three games. He has practiced and is expected to resume his early-down role, though the Chiefs remain one of the most pass-heavy teams in the league. He profiles as a low-end starter until his workload stabilizes.

Omarion Hampton is now designated to return from injured reserve after fracturing his left ankle earlier in the season. He participated in limited practice on Wednesday. The Chargers are expected to ease him back in, keeping Kimani Vidal relevant for Week 13 in most formats. Hampton’s full return timeline remains unclear.

Several other major names headline this week’s fantasy injury landscape. Josh Allen worked through elbow discomfort but is practicing fully. Jaylen Waddle returned in limited capacity after the Dolphins’ bye. C.J. Stroud has cleared concussion protocol and is trending toward playing, according to team officials reported by national outlets. Lamar Jackson has been removed from the injury report entirely.

Tee Higgins remains out with a concussion. Garrett Wilson remains on injured reserve and cannot return until Week 15. Alvin Kamara is expected to miss time with an MCL sprain, elevating rookie Devin Neal to the lead role in New Orleans. The Saints have also reported limited participation for Chris Olave due to a back injury.

The longer-term injury picture also affects Week 13 planning. Calvin Ridley is out for the season after a fibula fracture. Malik Nabers remains out for the year with a torn ACL. Travis Hunter is also finished for the season due to an LCL tear. These absences shape offensive roles across several teams.

Trusted outlets including Reuters and AP News have confirmed several of these injuries through team statements and league-wide coverage. These updates highlight how unpredictable late-season availability can become for fantasy managers.

How Week 13 Injuries Affect Upcoming Matchups

The biggest shifts this week relate to quarterbacks and running backs. Baker Mayfield’s expected absence reduces the passing ceiling for Chris Godwin and rookie Emeka Egbuka. Tampa Bay may lean more heavily on Bucky Irving as he ramps up from a long foot and shoulder rehab period.

Isiah Pacheco’s return helps stabilize the Chiefs’ backfield but does not guarantee high production, given Kansas City’s reliance on the passing game. Kimani Vidal’s role could remain steady even if Hampton is activated on Sunday, making him a safer FLEX play.

Josh Allen, C.J. Stroud, and Lamar Jackson returning at full participation restores confidence for fantasy managers relying on high-volume quarterbacks. However, missing weapons like Tee Higgins, Garrett Wilson, and Brandon Aiyuk continue to limit team offenses even when their quarterbacks return.

As fantasy playoffs approach, these Week 13 injury shifts matter more than ever. Lineups hinge on small updates, practice logs, and official team designations. Fantasy Football Injury Update Week 13 will continue to develop through Saturday as more statuses become final.

Fantasy Football Injury Update Week 13 will shape roster choices across all formats. Staying updated on official team reports remains essential as Sunday approaches. Managers should monitor late-week changes to avoid last-minute lineup issues.

FYI (keeping you in the loop)-

Q1: Which injuries matter most for Fantasy Football Injury Update Week 13?

Baker Mayfield, Isiah Pacheco, and Omarion Hampton headline the list. Quarterback updates for Josh Allen, C.J. Stroud, and Lamar Jackson are also important.

Q2: Will Isiah Pacheco play in Week 13?

Yes. He is expected to return after missing three games. His workload may be limited early.

Q3: Is Omarion Hampton going to be activated?

He has been designated to return, but the team will decide later in the week. He may need more time before resuming a full workload.

Q4: How does Baker Mayfield’s injury impact the Buccaneers?

Tampa Bay shifts to Teddy Bridgewater. It lowers the ceiling for all receivers and may increase reliance on the run game.

Q5: Which new injuries could affect fantasy playoffs?

Alvin Kamara’s MCL injury and Tee Higgins’ ongoing concussion absence could affect playoff seeding and weekly projections.