Fantasy football managers face critical lineup decisions heading into Week 10 of the 2025 NFL season. The running back landscape has shifted dramatically due to injuries and emerging workloads. This analysis provides clear start and sit recommendations to help optimize your roster.

According to ESPN, understanding backfield snap shares and matchups is crucial for success at this stage. The following breakdown focuses on players with significant opportunity or risk this weekend.
Start ‘Em: TreVeyon Henderson’s Favorable Matchup
New England Patriots rookie TreVeyon Henderson is a prime start candidate. He finally operated as the lead back last week. Henderson delivered a solid 12.5-point fantasy performance.
His matchup against the Tampa Bay Buccaneers is highly favorable. Tampa Bay allows the seventh-most fantasy points to opposing running backs. Even if Rhamondre Stevenson returns, Henderson’s role appears secure.
He should see double-digit touches regardless. Henderson projects as a strong RB2 with top-15 potential this week.
Sit ‘Em: The Tyrone Tracy Conundrum in New York
New York Giants running back Tyrone Tracy is a recommended sit. The anticipated lead role failed to materialize last Sunday. Tracy saw only eight touches and a 44% snap share.
Veteran Devin Singletary surprisingly led the backfield. This creates too much uncertainty for fantasy lineups. A tough matchup against the Chicago Bears further complicates matters.
Game script could work against Tracy if the Bears build an early lead. He is best left on benches until his role becomes clearer.
Start ‘Em: Kyle Monangai’s Momentum in Chicago
Chicago Bears rookie Kyle Monangai is a must-start after his breakout game. He exploded for 176 rushing yards and 22 receiving yards. Monangai showcased elite burst and vision.
While D’Andre Swift remains involved, Monangai has earned more work. He faces a New York Giants defense that is highly vulnerable. The Giants have allowed the third-most fantasy points to the position.
Monangai is a solid RB2 with significant upside. His recent performance warrants insertion into starting lineups.
Sit ‘Em: Avoiding Jacory Croskey-Merritt’s Struggles
Washington Commanders rookie Jacory Croskey-Merritt is a clear sit. He has failed to score more than six fantasy points in four straight games. His efficiency has plummeted recently.
The quarterback situation compounds the problem. With Jayden Daniels likely out, the offense may struggle. Negative game script could limit rushing attempts.
A matchup with the Detroit Lions presents a tough challenge. Croskey-Merritt cannot be trusted until he shows consistent production.
Making the correct RB start/sit decisions is vital for Week 10 fantasy football success. Focusing on matchup data and confirmed backfield roles provides the best path to victory. Always verify active/inactive statuses before finalizing your lineup.
Thought you’d like to know
Is TreVeyon Henderson a must-start RB for Week 10?
Yes, Henderson is a strong start. He has a great matchup and a secure role. He is a top RB2 option this week.
Why should I sit Tyrone Tracy?
His role is uncertain after a low snap share. The matchup and potential negative game script are also concerns. He is too risky to start.
Can Kyle Monangai be trusted after one big game?
His breakout performance suggests he has earned a larger role. The matchup is excellent, making him a reliable RB2.
What is the outlook for Jacory Croskey-Merritt?
His outlook is poor due to inefficiency and a bad offense. He should remain on benches until he shows improvement.
Where can I find more Week 10 fantasy advice?
Check major sports networks for updated rankings and analysis. Trusted sources provide comprehensive start/sit advice weekly.
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