‘Grey’s Anatomy’ New Season: Full Release Schedule for Season 22 Episodes

Grey’s Anatomy new season is finally here. Season 22 of the long-running medical drama premieres on October 9, 2025, bringing fresh storylines, emotional twists, and answers to major cliffhangers from last season’s explosive finale. Fans are eager to find out what happens next, especially as the fates of several key characters remain uncertain.

The new season continues the legacy of ABC’s hit series with 18 episodes scheduled to air weekly on Thursdays. Each episode will premiere at 10 p.m. EST on ABC and will be available to stream on Hulu the following day. This year’s storyline promises more drama, heartbreak, and surprises than ever before.

‘Grey’s Anatomy’ New Season Premiere Date and Episode Schedule

Season 22 of Grey’s Anatomy kicks off with the premiere episode, “Only the Strong Survive,” airing on Thursday, October 9, 2025. This episode picks up immediately after the season 21 finale’s shocking explosion inside Grey Sloan Memorial Hospital. The aftermath will reveal who survived and set the tone for the rest of the season.

Chris Carmack, who plays Dr. Atticus “Link” Lincoln, hinted that his character’s fate is still up in the air, adding even more suspense. In an interview earlier this year, Carmack admitted he hadn’t received confirmation about returning, suggesting that fans should prepare for anything.

Here’s the confirmed release schedule for the first half of Grey’s Anatomy Season 22:

• Episode 1: “Only the Strong Survive” — October 9, 2025
• Episode 2: “We Built This City” — October 16, 2025
• Episode 3: “Between Two Lungs” — October 23, 2025
• Episode 4: “Goodbye Horses” — October 30, 2025
• Episode 5: “Sometimes I Feel Like a Motherless Child” — November 6, 2025
• Episode 6: Title TBD — November 13, 2025
• Episode 7: Title TBD — November 20, 2025

The remaining episodes (8 through 18) will continue into 2026, with dates and titles to be announced by ABC in the coming months. Like previous seasons, breaks around major holidays are expected, and the season finale will likely air in spring 2026.

What to Expect from ‘Grey’s Anatomy’ Season 22

The new season promises to deliver the high-stakes drama fans have come to expect. The hospital will be dealing with the aftermath of the devastating explosion, and viewers will learn who lived, who died, and how the tragedy affects the lives of the doctors and patients at Grey Sloan Memorial.

Major storylines will include Jo’s desperate search for Link, Meredith’s continued medical research work, and new doctors joining the staff amid the chaos. The show’s creators have teased several emotional arcs that could redefine long-standing relationships and even introduce significant cast changes.

Fans should also prepare for intense ethical dilemmas, complex surgeries, and classic Grey’s Anatomy moments filled with love, loss, and resilience. The 22nd season could mark the beginning of a new era for the show as it approaches two decades on air.

Grey’s Anatomy new season is shaping up to be one of its most dramatic yet. With a thrilling premiere and weekly episodes packed with surprises, fans have plenty to look forward to in the months ahead.

FYI (keeping you in the loop)-

Q1: When does Grey’s Anatomy Season 22 premiere?

The first episode premieres on October 9, 2025, at 10 p.m. EST on ABC.

Q2: How many episodes are in Grey’s Anatomy Season 22?

Season 22 will feature 18 episodes airing weekly on Thursdays.

Q3: When are new episodes available on Hulu?

New episodes stream on Hulu the day after they air on ABC.

Q4: What is the storyline for Grey’s Anatomy Season 22?

The season explores the fallout from a hospital explosion and the uncertain fate of several key characters.

Q5: Is Chris Carmack returning as Link?

His return has not been confirmed, and his character’s fate remains uncertain.