Is Brock Purdy Playing Today? Latest Injury Update for 49ers QB vs. Cardinals

San Francisco 49ers quarterback Brock Purdy is officially set to return to action in Week 11 against the Arizona Cardinals. After missing several weeks due to a lingering turf toe injury, Purdy will reclaim his starting role Sunday afternoon at State Farm Stadium in Glendale, Arizona.

Head coach Kyle Shanahan confirmed on Friday that Purdy is ready to go after making progress in practice throughout the week. The decision ends Mac Jones’ short run as the team’s temporary starter, as the Niners look to bounce back from their tough loss to the Los Angeles Rams last weekend.

Brock Purdy Returns After Six-Week Absence

Purdy’s last appearance came in Week 4 before re-aggravating his turf toe, an injury sustained during the 49ers’ Week 1 win. In total, the young quarterback has appeared in only two games this season, leaving San Francisco to rely on backup Mac Jones through much of October and early November.

49ers general manager John Lynch hinted earlier in the week that the team was optimistic about Purdy’s return, saying that the quarterback had “turned a corner” in his rehab. Shanahan later confirmed that Purdy will start in Week 11, acknowledging that while the injury might not fully heal this year, the team feels confident in his readiness.

“He’s worked hard to get back,” Shanahan told reporters. “The toe isn’t 100 percent, but Brock gives us the best chance to win.”

Purdy’s comeback also carries some emotional weight. Born and raised in Arizona, the 24-year-old will be playing in front of friends and family as he looks to lead the 6-4 Niners to their seventh win of the season. The timing also works in the team’s favor — facing a 3-6 Cardinals squad that has struggled on both sides of the ball.

What Purdy’s Return Means for the 49ers

San Francisco’s offense has missed Purdy’s poise and consistency in recent weeks. While Mac Jones held his own, the 49ers’ passing efficiency dropped noticeably without their starter. With Purdy back under center, key playmakers like Deebo Samuel, Brandon Aiyuk, and George Kittle should see increased involvement, particularly in the intermediate passing game.

The team also expects smoother offensive rhythm and better red-zone execution — two areas that suffered during Purdy’s absence. Given how tight the NFC playoff picture is, Sunday’s matchup could mark a turning point for San Francisco as they aim to keep pace with the division-leading Seattle Seahawks.

Still, the 49ers are likely to monitor Purdy’s workload carefully. Turf toe injuries can be unpredictable, and with a crucial December stretch ahead, balancing recovery with performance will remain a top priority for the coaching staff.

Brock Purdy’s return marks a major boost for San Francisco’s playoff hopes. If he stays healthy, the 49ers could once again look like one of the NFC’s most dangerous teams.

FYI (keeping you in the loop)-

Q1: Is Brock Purdy playing today vs. the Cardinals?

Yes. Head coach Kyle Shanahan confirmed that Brock Purdy will start for the 49ers in Week 11 against the Arizona Cardinals.

Q2: When was Brock Purdy’s last game?

Purdy last played in Week 4 before aggravating his turf toe injury, sidelining him for more than a month.

Q3: Who started for the 49ers while Purdy was out?

Backup quarterback Mac Jones filled in for Purdy during his recovery, leading the 49ers through several midseason games.

Q4: How serious is Brock Purdy’s injury?

The turf toe is expected to linger through the season, but doctors cleared Purdy to play as long as pain and swelling remain manageable.

Q5: What time is the 49ers vs. Cardinals game?

The game kicks off Sunday, Nov. 16, at 4:05 p.m. ET at State Farm Stadium in Glendale, Arizona.