Jimmy Kimmel’s longtime bandleader, Cleto Escobedo III, has died. He was 59 years old. His passing occurred on November 11.
The musician’s death certificate has now disclosed the official cause. This provides clarity for his many friends and fans.

Medical Conditions Listed on Death Certificate
The immediate cause was cardiogenic shock. This is a rare condition where the heart suddenly cannot pump enough blood.
According to a copy of the death certificate obtained by TMZ, several underlying conditions contributed. These included vasodilatory shock and alcoholic cirrhosis of the liver. Disseminated intravascular coagulation was also listed.
Other significant factors were noted by medical officials. Sepsis, pneumonia, and chronic kidney disease were present. His condition was also complicated by being immunosuppressed.
Kimmel’s Heartfelt Tributes and Fundraising Efforts
Jimmy Kimmel recently paid an emotional tribute on his late-night show. He described Cleto as the kindest and most humble person.
Kimmel announced two fundraising initiatives in his friend’s memory. He started a fundraiser for UCLA Medical Center to help patients and families. Another was created for the Animal Foundation in their hometown of Las Vegas.
The host broke down while remembering his lifelong friend. He stated that everyone at the show was devastated by the loss. Kimmel said he felt more comfortable with Cleto than anyone else in his life.
The passing of Cleto Escobedo III has left a profound void in the entertainment community. His legacy continues through the charitable efforts launched in his name. The specific Cleto Escobedo cause of death highlights the serious nature of his health struggles.
Thought you’d like to know
What is cardiogenic shock?
Cardiogenic shock is a serious condition where the heart fails to pump enough blood. This can lead to organ failure. It is often a complication of a severe heart attack.
How long was Cleto Escobedo the bandleader on Jimmy Kimmel Live!?
Cleto Escobedo led the show’s house band for nearly the entire run. Jimmy Kimmel Live! has been on the air for almost 23 years. He was a foundational part of the program’s identity.
What were the underlying causes of his death?
His death certificate listed multiple underlying causes. These included alcoholic cirrhosis of the liver and vasodilatory shock. Other factors like sepsis and pneumonia were also contributing conditions.
How is Jimmy Kimmel honoring Cleto’s memory?
Kimmel has started two fundraising campaigns. One supports the UCLA Medical Center to aid families in financial need. The other benefits the Animal Foundation, reflecting Cleto’s love for animals.
Where did Jimmy Kimmel and Cleto Escobedo grow up?
The two were lifelong friends from the same neighborhood. They grew up together on the same street in Las Vegas. Their personal and professional relationship spanned decades.
Trusted Sources
TMZ, Jimmy Kimmel Live!
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