Joe Mixon Injury Update: Texans RB Sidelined for Key Games

Houston Texans running back Joe Mixon will miss at least the first four games of the season. He was placed on the Non-Football Injury (NFI) list ahead of the team’s opener. This is a significant blow to the Texans’ offensive plans for 2025.

The team confirmed the news following reports from multiple sources. Head coach DeMeco Ryans stated the team must move forward without its starting RB.

Texans Adjust Backfield Strategy Without Key Starter

Without Mixon, the Texans’ running game looked thin in a Week 1 loss to the Rams. The team now turns to a committee approach to fill the void. This group includes new addition Nick Chubb and holdover Dameon Pierce.

Rookie Woody Marks is also expected to see playing time. According to ProFootballNetwork, injury analyst Jeff Mueller received troubling information about Mixon’s status. The team has not provided a specific timeline for his return.

General Manager Nick Caserio addressed the situation cautiously. He said the team will evaluate Mixon after the four-week period ends. A determination on his playing status will be made at that time.

Impact on Houston’s High-Powered Offense

Mixon was a central figure in the Texans’ success last season. He rushed for over 1,000 yards and scored 12 regular-season touchdowns. His absence forces a major reshuffle for quarterback C.J. Stroud and the offense.

Nick Chubb is the most experienced back remaining on the roster. However, he is still working his way back from his own serious injuries. His early-down work will be crucial for the team’s balance.

The Texans face a tough early schedule without their top rusher. How the new backfield committee performs could define their season start.

Joe Mixon’s injury creates a major challenge for the Texans’ Super Bowl aspirations. His return timeline remains uncertain beyond the initial four-game absence. The team’s depth will be tested immediately.

Thought you’d like to know

What is the Non-Football Injury (NFI) list?

Players placed on the NFI list are unavailable due to injuries not sustained during official team activities. They must miss a minimum of four games. Their status is reevaluated after that period.

When can Joe Mixon return to play?

Mixon is eligible to return after the Texans’ fourth game. His actual return depends on his recovery progress and team evaluation. There is no guarantee he plays immediately after that.

Who will start at running back for the Texans?

Veteran Nick Chubb is expected to handle the majority of early-down work. Dameon Pierce and rookie Woody Marks will also share carries. The team will likely use a running back by committee approach.

How did Joe Mixon perform last season?

Mixon had a stellar first year with Houston in 2024. He rushed for 1,016 yards and 11 touchdowns. He also added 36 receptions for 309 yards and another score.