Houston Texans running back Joe Mixon will miss the entire 2025 NFL season. The Pro Bowl player has been sidelined by a persistent foot injury since training camp. Multiple reports from NFL Media and ESPN confirm his season-ending status.

The Texans placed Mixon on the Non-Football Injury list in late July. Team officials have described the situation as ambiguous throughout the process.
From Offseason Workouts to Season-Ending Absence
Mixon first appeared on the injury report during offseason activities. He missed organized team activities and minicamp practices. Team sources initially indicated an ankle issue.
The situation escalated when training camp opened. Mixon was immediately placed on the NFI list. This move made him ineligible to practice or play.
General Manager Nick Caserio addressed the media in August. He called the injury situation “very gray” and lacking clarity. The team provided no specific timeline for Mixon’s potential return.
Texans’ Backfield Adjustments Without Their Star
Houston moved quickly to address the running back vacancy. The team signed veteran Nick Chubb shortly after Mixon’s NFI designation. They also drafted rookie Woody Marks for additional depth.
Chubb has started eight games in Mixon’s absence. He has accumulated 419 rushing yards through mid-season. Marks has shown promise with 538 scrimmage yards.
The Texans struggled initially without their lead back. They lost their first three games of the season. The team has since improved to a .500 record.
Contract Implications and Future Uncertainty
Mixon’s extended absence raises questions about his future. The 29-year-old signed a three-year contract extension in 2024. His cap hit for 2026 remains significant.
According to ESPN analysts, the Texans could consider restructuring his deal. The team may seek additional medical clarity before making decisions. Mixon’s age and injury history factor into these considerations.
The running back market continues evolving across the league. Teams are increasingly cautious about long-term commitments to veteran runners.
Communication Breakdown Frustrates Fans and Analysts
The Texans have maintained remarkable secrecy around Mixon’s condition. Coach DeMeco Ryans repeatedly deflected questions about the injury. His standard response became “I do not” when asked for updates.
This approach has frustrated fans and media members alike. The lack of transparency has spawned numerous theories online. Team officials have declined to specify when or how the injury occurred.
NFL Media reported the injury happened away from team facilities. This explains the Non-Football Injury designation. Beyond this basic information, details remain scarce.
The Joe Mixon injury situation represents one of the season’s most puzzling stories. His complete absence has forced the Texans to reinvent their rushing attack. The mystery surrounding his foot injury continues unresolved.
Thought you’d like to know
What is the Non-Football Injury list?
The NFI list is for players who get injured away from team activities. These players don’t count against the 53-man roster. They must miss at least the first four games.
How has Joe Mixon performed with the Texans?
Mixon had an excellent 2024 season in Houston. He rushed for 1,016 yards and scored 11 touchdowns. His performance earned him Pro Bowl honors.
Who is replacing Mixon in the lineup?
Veteran Nick Chubb has started most games. Rookie Woody Marks has seen increased playing time recently. The Texans are using a committee approach.
Could Mixon return in 2025?
Multiple reports indicate Mixon won’t play this season. The Texans haven’t officially ruled him out. Team sources suggest a return is highly unlikely.
What does this mean for Mixon’s career?
At 29, missing a full season is significant. The Texans will likely evaluate his health thoroughly. His contract situation makes this offseason crucial.
How has the offense changed without Mixon?
Houston’s running game has been inconsistent. They rank in the bottom half of the league in rushing. The passing game has carried more of the offensive load.
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