Mac Jones Injury Update: Will the 49ers QB Play Against the Cardinals in Week 11?

Mac Jones enters Week 11 after a strong performance, and the main question for San Francisco fans is whether he will be available against the Arizona Cardinals. The Mac Jones injury update shows he was a full participant in practice and does not carry an injury designation. The 49ers face Arizona on Nov. 16 at State Farm Stadium.

The matchup carries major importance for San Francisco as Jones continues one of his most efficient seasons. His knee issue appeared earlier in the week, but team reports show no setback and no limitation heading into the division meeting. That has eased concerns for 49ers fans hoping to keep momentum against a struggling Cardinals defense.

Latest Mac Jones Injury Update Ahead of 49ers vs. Cardinals

San Francisco listed Mac Jones on the injury report with a knee issue, but he practiced fully throughout the week. According to team updates and league injury logs, Jones does not have a game status designation for Sunday. That typically means he is expected to play unless an unexpected setback occurs. This aligns with standard injury-report procedures used by the league and covered widely by outlets such as Associated Press and Reuters.

Jones is coming off a standout Week 10 performance with 319 passing yards, three touchdowns, and only one interception. His timing, accuracy, and mid-range passing helped San Francisco secure a convincing win against the Rams. His 69.6% completion rate this season is one of the best of his career, showing his improved rhythm in the 49ers system.

Through nine games, Jones has thrown for 2,151 yards and 13 touchdowns while adding 64 rushing yards on designed runs and scrambles. He is averaging 268.9 passing yards per game, giving the 49ers stability and efficiency in the air. His earlier performances this season include three multi-touchdown games and strong outings against the Saints, Rams, and Giants.

The Cardinals defense has struggled with consistency in coverage, making Jones a key factor in the 49ers game plan. If he plays at his recent level, San Francisco will have a strong advantage through the air.

What This Means for the 49ers’ Week 11 Outlook

The Mac Jones injury update is a relief for San Francisco, which has leaned heavily on Jones’ accuracy and decision-making. A healthy Jones helps maintain offensive continuity and reduces pressure on the ground game, especially in early drives.

The 49ers are fighting to stay in control of the NFC playoff race. A road game against the Cardinals is a chance to extend their winning streak, and having Jones healthy improves their chances. The team has seen major ups and downs throughout the season, but Jones’ efficiency has been a steadying factor.

The latest Mac Jones injury update signals good news for San Francisco. With full participation in practice and no game-day designation, the 49ers expect Jones to start in Week 11. His recent momentum and strong command of the offense set the stage for another big performance.

FYI (keeping you in the loop)-

Q1: Is Mac Jones playing in Week 11?

Yes. The latest Mac Jones injury update shows he practiced fully and carries no injury designation. He is expected to start against the Cardinals.

Q2: What was Mac Jones’ latest injury status?

He was listed with a knee issue early in the week. He practiced fully and appears cleared to play.

Q3: How has Mac Jones performed this season?

Jones has 2,151 yards and 13 touchdown passes. He is completing nearly 70% of his throws and has multiple high-yardage games.

Q4: Why is Jones important for the 49ers’ Week 11 matchup?

His accuracy and recent momentum give the 49ers a strong advantage against a Cardinals defense that struggles in coverage.

Q5: When and where is the 49ers vs. Cardinals game?

The game is on Nov. 16 at 4:05 p.m. ET at State Farm Stadium. It airs on FOX.