NCAA Football Week 2 Schedule: Michigan vs Oklahoma, Iowa vs Iowa State, Kansas vs Missouri, Notre Dame Bye, Top 25 Games & AP Poll Updates

Week 2 of NCAA football brings fans a full slate of rivalry games, top-25 matchups, and key playoff storylines. The action is set across the country, but Notre Dame will not play this weekend, taking an early bye before its home opener against Texas A&M.

The spotlight falls on Michigan vs Oklahoma in Norman, Iowa vs Iowa State in a heated in-state clash, and the return of the Kansas vs Missouri Border War. Top 25 teams look to stay perfect as playoff talks slowly begin to form.

Michigan vs Oklahoma Headlines Week 2

No. 15 Michigan visits No. 18 Oklahoma in the weekend’s biggest game. Freshman quarterback Bryce Underwood leads the Wolverines after a strong debut in Week 1. He faces John Mateer, a Washington State transfer now starting for Oklahoma.

Both programs carry high expectations. Michigan is chasing Big Ten glory with a new star under center. Oklahoma is looking to bounce back from its rough SEC debut last season. Kickoff is at 7:30 p.m. ET on ABC.

Iowa Rivalry and Border War Return

Iowa meets Iowa State at noon ET on Fox. It is one of the most intense in-state rivalries in college football. Iowa coach Kirk Ferentz is chasing the all-time Big Ten wins record, while the Cyclones aim for a Big 12 title run.

The Border War also returns as Kansas battles Missouri at 3:30 p.m. ET on ESPN2. This rivalry has been off the calendar since 2011, when Missouri moved to the SEC. Fans expect a fiery contest fueled by decades of animosity dating back to the Civil War era.

Other Key Week 2 Games

No. 6 Oregon hosts Oklahoma State at 3:30 p.m. ET on CBS. The Ducks are heavy favorites, but star linebacker Bryce Boettcher is a player to watch. Oklahoma State coach Mike Gundy faces pressure after a poor 2024 season, raising questions about his future.

Penn State takes on FIU as Nick Singleton and Kaytron Allen continue their shared backfield dominance. LSU, Florida State, and Ohio State also look to keep their playoff paths clear. According to Associated Press updates, Ohio State has climbed to No. 1 in the AP Poll after an easy Week 1 win.

Notre Dame sits out this week after a Sunday game at Miami. The Irish return to face Texas A&M in a prime-time top-25 clash in South Bend.

NCAA football Week 2 delivers rivalries, blue-blood clashes, and playoff implications. Fans can expect drama, tradition, and storylines that shape the season.

Info at your fingertips-

Q1: What is the top NCAA football Week 2 game?

The biggest matchup is Michigan vs Oklahoma. Both teams are ranked in the top 25 and feature new quarterbacks.

Q2: Why is Notre Dame not playing in Week 2?

Notre Dame has an early bye week. The Irish return next weekend against Texas A&M in a home prime-time matchup.

Q3: Which rivalry returns in Week 2?

The Kansas vs Missouri Border War returns after 14 years. It remains one of the most bitter rivalries in college sports.

Q4: Who is No. 1 in the AP Top 25?

Ohio State is ranked No. 1 in the AP Poll after Week 1. LSU was also ranked first by some analysts.

Q5: What other key games should fans watch?

Iowa vs Iowa State, Oregon vs Oklahoma State, and Penn State vs FIU are among the other highlights. Each carries playoff or rivalry implications.