The NFL Week 10 injury tracker brings crucial updates for teams and fantasy football players alike. San Francisco 49ers quarterback Brock Purdy is reportedly “getting closer” to returning, while Washington Commanders rookie Jayden Daniels has avoided elbow surgery — a positive sign for his long-term availability this season.
Both updates highlight how injuries continue to shape the midseason playoff picture across the league, affecting team strategies and fantasy outcomes heading into a critical weekend of matchups.
Key Week 10 Injury Details Across the NFL
49ers head coach Kyle Shanahan confirmed that Brock Purdy, sidelined since Week 4 with a toe injury, continues to progress. “He’s definitely getting better each week, heading in the right direction,” Shanahan said. Purdy has remained limited in practice, but the team has yet to make a final call on his availability for Sunday’s game against the Rams. Mac Jones will again start if Purdy is ruled out.
Meanwhile, Washington Commanders quarterback Jayden Daniels received encouraging news following an MRI on his elbow. Reports indicate there’s no ligament damage and no need for surgery. Daniels won’t be placed on injured reserve and will be re-evaluated after Washington’s Week 12 bye. The Commanders believe the dual-threat passer could return before season’s end, depending on recovery progress.
Elsewhere, several key players headline Week 10’s injury report. Houston Texans quarterback C.J. Stroud remains sidelined due to a concussion sustained in Week 9, leaving Davis Mills as the starter. Cornerback Sauce Gardner has cleared concussion protocol and is set to make his Indianapolis Colts debut against Atlanta following his trade from the New York Jets.
In Philadelphia, running back Saquon Barkley returned to practice after a groin issue but remains uncertain for Monday’s game. Wide receiver A.J. Brown, who missed Week 8, said he expects to play. The Tampa Bay Buccaneers, however, will remain without Chris Godwin Jr. (fibula) and Bucky Irving (foot, shoulder) for another week.
Broader Fantasy and Team Implications
From a fantasy football perspective, Purdy’s nearing return could significantly boost the value of Deebo Samuel and Brandon Aiyuk, whose production has dipped under backup quarterback Mac Jones. Jayden Daniels’ recovery keeps hope alive for fantasy managers banking on his dual-threat upside later in the season.
The Texans’ situation with Stroud impacts Tank Dell and Nico Collins owners, as Davis Mills is expected to take a more conservative approach offensively. For the Eagles, Barkley’s potential comeback could spark renewed explosiveness in an offense that struggled for balance before the bye.
Defensively, Sauce Gardner’s return adds depth to a Colts unit in need of secondary stability. His first appearance in a new uniform will draw attention during the team’s international game in Berlin.
As Week 10 unfolds, the NFL injury tracker continues to shape team momentum, fantasy decisions, and playoff positioning across the league. With Purdy close to returning and Daniels escaping surgery, both teams received much-needed optimism moving forward.
FYI (keeping you in the loop)-
Q1: Will Brock Purdy play in Week 10?
As of Saturday, Purdy remains limited in practice and is unlikely to play this week, though he’s nearing a return soon.
Q2: What is Jayden Daniels’ recovery timeline?
Daniels avoided surgery and will be re-evaluated after the Commanders’ Week 12 bye, leaving a chance for a late-season return.
Q3: Who replaces C.J. Stroud for the Texans?
Davis Mills will start in place of Stroud for Houston’s Week 10 matchup against Jacksonville.
Q4: Which big names are ruled out for Week 10?
Chris Godwin Jr., Bucky Irving, Rhamondre Stevenson, and DeForest Buckner headline those ruled out this week.
Q5: How does this affect fantasy football?
Managers should bench injured players like Stroud and Barkley (if inactive) and monitor backup performances closely.
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