Week 17 presents a critical crossroads for fantasy football managers. Picking the right quarterback can make or break a championship bid. This week’s slate features several players with standout matchups poised for big scoring outputs.

Identifying high-upside options is key as the postseason pressure mounts. Based on matchup data and recent performance trends, here are the top quarterback starts to secure your victory.
Analyzing the Prime Week 17 Matchups
Jacoby Brissett of the Arizona Cardinals faces a favorable road test. He plays the Cincinnati Bengals, a defense that allows the fifth-most fantasy points per game to quarterbacks. Brissett’s primary weapon, receiver Marvin Harrison Jr., is also expected back at full health. This combination sets the stage for a strong bounce-back performance.
San Francisco’s Brock Purdy is on a blistering hot streak. He has thrown for 295 yards and three or more touchdowns in two consecutive games. In Week 17, he meets a Chicago Bears defense that has allowed the third-most passing touchdowns this season. Purdy’s dual-threat capability adds significant fantasy upside against this unit.
Rookie Talent and Strategic Streamers
Chicago’s Caleb Williams represents a high-ceiling play. The rookie faces an injury-diminished San Francisco 49ers defense that just allowed veteran Philip Rivers a productive day. Williams has thrown multiple touchdown passes in three straight games. His rushing ability provides a stable floor even in a tough road environment.
New Orleans Saints rookie Tyler Shough is a premier streaming option. He has scored 17 or more fantasy points in four consecutive starts. His Week 17 opponent, the Tennessee Titans, allows the seventh-most fantasy points to opposing quarterbacks. Shough’s mobility makes him particularly dangerous against this vulnerable defense.
Finalizing your Week 17 lineup requires trusting the data. Targeting these high-matchup quarterbacks provides the clearest path to a fantasy football championship victory.
Info at your fingertips
Is Jacoby Brissett a reliable starter for the fantasy finals?
Yes, especially this week. His matchup against the Bengals is one of the best on the board. Cincinnati’s defense consistently allows high passing numbers and touchdowns.
Why is Brock Purdy ranked so high this week?
Purdy is in elite form with back-to-back huge games. The Bears’ defense, while creating turnovers, has been generous to quarterbacks in terms of yards and scores. He is a top-tier option.
Can I trust rookie Caleb Williams in a playoff game?
His recent consistency makes him trustworthy. Williams has multiple touchdowns in three straight games and adds value with his legs. The 49ers’ defense is not the intimidating unit it once was.
What makes Tyler Shough a viable streamer?
Shough offers a high floor with his rushing ability and faces the Titans’ weak pass defense. He has been a steady producer for over a month, making him a safe, high-upside play.
Who is the safest QB start for Week 17?
Brock Purdy is likely the safest due to his elite supporting cast and current form. Jacoby Brissett also offers a very safe floor due to the sheer quality of his opponent’s defense.
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