Fantasy football managers face critical lineup decisions heading into Week 10 of the 2025 NFL season. Key matchups and recent player performances are creating new start and sit scenarios. Several wide receivers are emerging as must-starts while others face difficult situations.

According to ESPN analysis, target shares and quarterback rapport have solidified nearly halfway through the season. This provides clearer data for making informed fantasy decisions during the crucial playoff push period.
Start These Wide Receivers in Week 10
Alec Pierce of the Indianapolis Colts presents strong start potential against the Atlanta Falcons. Pierce has seen a dramatic increase in targets over the past three games. He has transformed from a deep threat into a consistent receiving option.
The Falcons secondary has shown recent vulnerabilities after a strong start to the season. Atlanta just allowed substantial production to New England’s secondary receiver DeMario Douglas. This matchup sets up favorably for Pierce to continue his upward trend.
Green Bay’s Romeo Doubs also deserves starting consideration despite quarterback concerns. Doubs has maintained consistent production regardless of the Packers’ offensive struggles. His target volume remains among the league’s highest for primary receivers.
Los Angeles Chargers receiver Quentin Johnston offers touchdown upside against the Steelers. Pittsburgh’s defense ranks among the worst against fantasy wide receivers this season. Johnston’s big-play ability makes him a volatile but potentially rewarding start.
Wide Receivers to Bench This Week
Jacksonville’s Parker Washington faces multiple obstacles in Week 10. The Jaguars recently acquired veteran receiver Jakobi Meyers, which could immediately impact Washington’s role. His previous target share appears unsustainable with the new addition.
Houston’s defense presents another challenge for Washington’s fantasy prospects. The Texans have limited opposing passing games effectively throughout the season. This combination of factors makes Washington a risky play.
New Orleans star Chris Olave represents the most surprising sit recommendation. The Saints’ quarterback change to rookie Tyler Shough has dramatically affected Olave’s production. His massive target share from earlier games has disappeared under the new quarterback.
Carolina’s strong pass defense further complicates Olave’s outlook. The Panthers have consistently limited fantasy production from opposing receivers. Even elite talents like Olave struggle against this caliber of defensive performance.
Week 10 presents both opportunity and risk for fantasy receivers. Making the right start/sit decisions could determine playoff chances. Always consider matchups and recent trends before setting lineups.
Thought you’d like to know
Why should I start Alec Pierce this week?
Pierce has seen 28 targets over his last three games. The Falcons defense has struggled against secondary receivers recently.
Is Chris Olave really a sit this week?
Yes, the quarterback change to Tyler Shough has reduced Olave’s targets significantly. Carolina’s strong pass defense makes the matchup particularly difficult.
What makes Quentin Johnston a good start?
Johnston has scored six touchdowns this season despite inconsistent targets. The Steelers allow the second-most fantasy points to wide receivers.
Will Parker Washington’s role change?
Jacksonville’s acquisition of Jakobi Meyers likely reduces Washington’s targets. The Texans’ strong pass defense creates additional concerns.
How reliable is Romeo Doubs?
Doubs has scored double-digit fantasy points in four of his last five games. His consistent target share makes him relatively safe despite Green Bay’s offensive struggles.
Trusted Sources
ESPN, NFL Network, Associated Press, Reuters
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